Premature Ovarian Failure

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Premature Ovarian Failure or primary ovarian failure is an uncommon condition that may affect women of reproductive age, mostly under 40. The condition leads to infertility and is often a difficult situation to deal with for most women. 

Since premature ovarian failure is a rare condition, women diagnosed with it may not fully understand how the condition will affect them and how they can deal with it. 

We at Giggles Hospitals for Best Women And Children Hospital in Vizag ,provide counselling and guidance along with medical treatment to help women manage the symptoms and complications associated with premature ovarian failure or primary ovarian insufficiency.

Premature Ovarian Failure

Premature Ovarian Failure is a rare condition in which women undergo menopause before the age of 40. The condition is more popularly known as primary ovarian failure or primary ovarian insufficiency.

In this condition, the ovaries suddenly stop functioning as they should before age 40. Consequently, the body cannot produce the required hormones for a normal menstrual cycle which often leads to infertility.

Premature ovarian failure is not an easy diagnosis to live with especially since it leads to infertility and is mostly permanent. Women who may still want to expand their family and conceive will need emotional support and counselling if they have been diagnosed with Premature ovarian failure.


Premature ovarian failure symptoms are mostly similar to that of menopause and oestrogen deficiency. These mainly include the following:

  1. Irregular or absent menstrual periods
  2. Hot flashes and night sweats
  3. Vaginal dryness
  4. Mood swings and irritability
  5. Decreased sex drive
  6. Difficulty conceiving or infertility
  7. Fatigue and lack of energy
  8. Trouble sleeping
  9. Cognitive changes such as difficulty with memory or concentration
  10. Joint and muscle pain

It’s important to note that the symptoms may vary among individuals, and not all women will experience all of these symptoms.


The exact cause of Premature Ovarian Failure is not known. However, research indicates that most cases of premature ovarian failure may have contributing genetic factors. Factors that can contribute to the occurrence of premature ovarian failure include the following:

  • Genetic factors and chromosomal abnormalities
  • Autoimmune disorders, where the body’s immune system mistakenly attacks the ovarian tissue
  • Certain medical treatments such as chemotherapy or radiation therapy
  • Premature ageing of the ovaries
  • Hysterectomy 
  • Environmental factors or toxins i.e. long-term exposure to chemicals, pesticides, cigarette smoke, and various toxins
  • Hormonal imbalances
  • Certain medical conditions like Turner syndrome or Fragile X syndrome
  • Family history 
  • Certain infections or diseases

Diagnosing Premature Ovarian Failure at Giggles Hospital

To diagnose premature ovarian failure, doctors will perform a physical exam and some tests to check your hormonal levels and rule out other possible causes. Following are some general steps taken to diagnose premature ovarian failure:

  1. Physical exam
  2. Medical history evaluation
  3. Pelvic exam
  4. Blood tests (karyotype testing) 
  5. Hormone level testing 
  6. Pelvic ultrasound 
  7. Pregnancy test.
  8. Antibody test

Treatment for Premature Ovarian Failure at Giggles Hospital

Unfortunately, premature ovarian failure is permanent and cannot be reversed. However, if a woman has been diagnosed with premature ovarian failure, doctors may recommend the following ways to manage the symptoms and reduce the risk of further complications.

  1. Hormone replacement therapy (HRT) or Oestrogen Therapy
  2. Vitamin supplements

If someone has a biological parent who went through premature ovarian failure, we do recommend them to pursue fertility preservation if they wish to have children and there is an increased risk of premature ovarian failure for them in the future.

Why Choose Giggles Hospitals?

Giggles Hospitals for Gynecology doctor near me are renowned for its specialised and evidence-based approach to managing premature ovarian failure. Our expert team of reproductive endocrinologists provides tailored treatment plans, which may include hormone replacement therapy, assisted reproductive techniques, and ongoing monitoring to optimise patient outcomes and enhance fertility possibilities. With our compassionate care and cutting-edge resources, we are dedicated to supporting individuals with premature ovarian failure on their journey toward reproductive health and family-building aspirations.

Our Doctors

Dr. Batchu Sowdamini

Senior Consultant Obstetrician and Gynaecologist View Profile
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Dr. Radhika Jupally

Gynecologist and Obstetrician View Profile
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Dr. Padmaja S

Gynaecologist and Obstetrician View Profile
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Frequently Asked Questions

Premature ovarian failure cannot be prevented, but certain factors such as avoiding smoking and maintaining a healthy lifestyle may lower the risk.

While stress and lifestyle factors may influence overall health, there is limited evidence to suggest a direct link between them and the development of premature ovarian failure.

Yes, Hormone Replacement Therapy (HRT) can effectively manage symptoms of premature ovarian failure by replacing the hormones that the ovaries no longer produce, providing relief and reducing associated health risks.

Pregnancy without medical intervention is unlikely in cases of premature ovarian failure, as it is associated with infertility due to the loss of normal ovarian function. If you are at risk of premature ovarian failure, talk to our doctors at Giggles Hospital for Best women's hospital near me about possible options for you if you wish to get pregnant.

Premature ovarian failure is often associated with autoimmune disorders, genetic abnormalities, and certain chromosomal disorders such as Turner syndrome.